diff --git a/packages/nodes-base/nodes/Github/GithubTrigger.node.ts b/packages/nodes-base/nodes/Github/GithubTrigger.node.ts
index 09da267953..2dc53ee6c6 100644
--- a/packages/nodes-base/nodes/Github/GithubTrigger.node.ts
+++ b/packages/nodes-base/nodes/Github/GithubTrigger.node.ts
@@ -352,7 +352,17 @@ export class GithubTrigger implements INodeType {
 					active: true,
 				};
 
-				const responseData = await githubApiRequest.call(this, 'POST', endpoint, body);
+
+				let responseData;
+				try {
+					responseData = await githubApiRequest.call(this, 'POST', endpoint, body);
+				} catch (e) {
+					if (e.message.includes('[422]:')) {
+						throw new Error('A webhook with the identical URL exists already. Please delete it manually on Github!');
+					}
+
+					throw e;
+				}
 
 				if (responseData.id === undefined || responseData.active !== true) {
 					// Required data is missing so was not successful