diff --git a/cmd/prometheus/main.go b/cmd/prometheus/main.go
index 6160741ef..2b7038138 100644
--- a/cmd/prometheus/main.go
+++ b/cmd/prometheus/main.go
@@ -387,9 +387,9 @@ func main() {
 	)
 
 	cfg.web.Context = ctxWeb
-	cfg.web.TSDB = localStorage.Get
 	cfg.web.TSDBRetentionDuration = cfg.tsdb.RetentionDuration
 	cfg.web.TSDBMaxBytes = cfg.tsdb.MaxBytes
+	cfg.web.LocalStorage = localStorage
 	cfg.web.Storage = fanoutStorage
 	cfg.web.QueryEngine = queryEngine
 	cfg.web.ScrapeManager = scrapeManager
@@ -921,14 +921,7 @@ func (s *readyStorage) Set(db *tsdb.DB, startTimeMargin int64) {
 	s.startTimeMargin = startTimeMargin
 }
 
-// Get the storage.
-func (s *readyStorage) Get() *tsdb.DB {
-	if x := s.get(); x != nil {
-		return x
-	}
-	return nil
-}
-
+// get is internal, you should use readyStorage as the front implementation layer.
 func (s *readyStorage) get() *tsdb.DB {
 	s.mtx.RLock()
 	x := s.db
@@ -983,12 +976,44 @@ func (n notReadyAppender) Rollback() error { return tsdb.ErrNotReady }
 
 // Close implements the Storage interface.
 func (s *readyStorage) Close() error {
-	if x := s.Get(); x != nil {
+	if x := s.get(); x != nil {
 		return x.Close()
 	}
 	return nil
 }
 
+// CleanTombstones implements the api_v1.TSDBAdminStats and api_v2.TSDBAdmin interfaces.
+func (s *readyStorage) CleanTombstones() error {
+	if x := s.get(); x != nil {
+		return x.CleanTombstones()
+	}
+	return tsdb.ErrNotReady
+}
+
+// Delete implements the api_v1.TSDBAdminStats and api_v2.TSDBAdmin interfaces.
+func (s *readyStorage) Delete(mint, maxt int64, ms ...*labels.Matcher) error {
+	if x := s.get(); x != nil {
+		return x.Delete(mint, maxt, ms...)
+	}
+	return tsdb.ErrNotReady
+}
+
+// Snapshot implements the api_v1.TSDBAdminStats and api_v2.TSDBAdmin interfaces.
+func (s *readyStorage) Snapshot(dir string, withHead bool) error {
+	if x := s.get(); x != nil {
+		return x.Snapshot(dir, withHead)
+	}
+	return tsdb.ErrNotReady
+}
+
+// Stats implements the api_v1.TSDBAdminStats interface.
+func (s *readyStorage) Stats(statsByLabelName string) (*tsdb.Stats, error) {
+	if x := s.get(); x != nil {
+		return x.Head().Stats(statsByLabelName), nil
+	}
+	return nil, tsdb.ErrNotReady
+}
+
 // tsdbOptions is tsdb.Option version with defined units.
 // This is required as tsdb.Option fields are unit agnostic (time).
 type tsdbOptions struct {
diff --git a/promql/test.go b/promql/test.go
index 72dd9b9b8..e3d99e83f 100644
--- a/promql/test.go
+++ b/promql/test.go
@@ -25,10 +25,10 @@ import (
 
 	"github.com/pkg/errors"
 	"github.com/prometheus/common/model"
-
 	"github.com/prometheus/prometheus/pkg/labels"
 	"github.com/prometheus/prometheus/promql/parser"
 	"github.com/prometheus/prometheus/storage"
+	"github.com/prometheus/prometheus/tsdb"
 	"github.com/prometheus/prometheus/util/teststorage"
 	"github.com/prometheus/prometheus/util/testutil"
 )
@@ -54,7 +54,7 @@ type Test struct {
 
 	cmds []testCommand
 
-	storage storage.Storage
+	storage *teststorage.TestStorage
 
 	queryEngine *Engine
 	context     context.Context
@@ -101,6 +101,11 @@ func (t *Test) Storage() storage.Storage {
 	return t.storage
 }
 
+// TSDB returns test's TSDB.
+func (t *Test) TSDB() *tsdb.DB {
+	return t.storage.DB
+}
+
 func raise(line int, format string, v ...interface{}) error {
 	return &parser.ParseErr{
 		LineOffset: line,
diff --git a/tsdb/db.go b/tsdb/db.go
index 9ab1124d6..e97499c04 100644
--- a/tsdb/db.go
+++ b/tsdb/db.go
@@ -39,6 +39,7 @@ import (
 	"github.com/prometheus/prometheus/tsdb/chunkenc"
 	tsdb_errors "github.com/prometheus/prometheus/tsdb/errors"
 	"github.com/prometheus/prometheus/tsdb/fileutil"
+
 	// Load the package into main to make sure minium Go version is met.
 	_ "github.com/prometheus/prometheus/tsdb/goversion"
 	"github.com/prometheus/prometheus/tsdb/wal"
diff --git a/tsdb/head.go b/tsdb/head.go
index 8da6fc2be..4b374fd5d 100644
--- a/tsdb/head.go
+++ b/tsdb/head.go
@@ -751,6 +751,23 @@ func (h *Head) initTime(t int64) (initialized bool) {
 	return true
 }
 
+type Stats struct {
+	NumSeries         uint64
+	MinTime, MaxTime  int64
+	IndexPostingStats *index.PostingsStats
+}
+
+// Stats returns important current HEAD statistics. Note that it is expensive to
+// calculate these.
+func (h *Head) Stats(statsByLabelName string) *Stats {
+	return &Stats{
+		NumSeries:         h.NumSeries(),
+		MaxTime:           h.MaxTime(),
+		MinTime:           h.MinTime(),
+		IndexPostingStats: h.PostingsCardinalityStats(statsByLabelName),
+	}
+}
+
 type RangeHead struct {
 	head       *Head
 	mint, maxt int64
diff --git a/util/teststorage/storage.go b/util/teststorage/storage.go
index c6ac4b89a..6fa90781e 100644
--- a/util/teststorage/storage.go
+++ b/util/teststorage/storage.go
@@ -18,14 +18,13 @@ import (
 	"os"
 	"time"
 
-	"github.com/prometheus/prometheus/storage"
 	"github.com/prometheus/prometheus/tsdb"
 	"github.com/prometheus/prometheus/util/testutil"
 )
 
-// New returns a new storage for testing purposes
+// New returns a new TestStorage for testing purposes
 // that removes all associated files on closing.
-func New(t testutil.T) storage.Storage {
+func New(t testutil.T) *TestStorage {
 	dir, err := ioutil.TempDir("", "test_storage")
 	if err != nil {
 		t.Fatalf("Opening test dir failed: %s", err)
@@ -40,16 +39,16 @@ func New(t testutil.T) storage.Storage {
 	if err != nil {
 		t.Fatalf("Opening test storage failed: %s", err)
 	}
-	return testStorage{Storage: db, dir: dir}
+	return &TestStorage{DB: db, dir: dir}
 }
 
-type testStorage struct {
-	storage.Storage
+type TestStorage struct {
+	*tsdb.DB
 	dir string
 }
 
-func (s testStorage) Close() error {
-	if err := s.Storage.Close(); err != nil {
+func (s TestStorage) Close() error {
+	if err := s.DB.Close(); err != nil {
 		return err
 	}
 	return os.RemoveAll(s.dir)
diff --git a/web/api/v1/api.go b/web/api/v1/api.go
index b94c91944..a0ae68527 100644
--- a/web/api/v1/api.go
+++ b/web/api/v1/api.go
@@ -37,7 +37,6 @@ import (
 	"github.com/prometheus/client_golang/prometheus"
 	"github.com/prometheus/common/model"
 	"github.com/prometheus/common/route"
-
 	"github.com/prometheus/prometheus/config"
 	"github.com/prometheus/prometheus/pkg/gate"
 	"github.com/prometheus/prometheus/pkg/labels"
@@ -159,13 +158,13 @@ type apiFuncResult struct {
 
 type apiFunc func(r *http.Request) apiFuncResult
 
-// TSDBAdmin defines the tsdb interfaces used by the v1 API for admin operations.
-type TSDBAdmin interface {
+// TSDBAdminStats defines the tsdb interfaces used by the v1 API for admin operations as well as statistics.
+type TSDBAdminStats interface {
 	CleanTombstones() error
 	Delete(mint, maxt int64, ms ...*labels.Matcher) error
-	Dir() string
 	Snapshot(dir string, withHead bool) error
-	Head() *tsdb.Head
+
+	Stats(statsByLabelName string) (*tsdb.Stats, error)
 }
 
 // API can register a set of endpoints in a router and handle
@@ -183,7 +182,8 @@ type API struct {
 	ready                 func(http.HandlerFunc) http.HandlerFunc
 	globalURLOptions      GlobalURLOptions
 
-	db                        func() TSDBAdmin
+	db                        TSDBAdminStats
+	dbDir                     string
 	enableAdmin               bool
 	logger                    log.Logger
 	remoteReadSampleLimit     int
@@ -209,7 +209,8 @@ func NewAPI(
 	flagsMap map[string]string,
 	globalURLOptions GlobalURLOptions,
 	readyFunc func(http.HandlerFunc) http.HandlerFunc,
-	db func() TSDBAdmin,
+	db TSDBAdminStats,
+	dbDir string,
 	enableAdmin bool,
 	logger log.Logger,
 	rr rulesRetriever,
@@ -232,6 +233,7 @@ func NewAPI(
 		ready:                     readyFunc,
 		globalURLOptions:          globalURLOptions,
 		db:                        db,
+		dbDir:                     dbDir,
 		enableAdmin:               enableAdmin,
 		rulesRetriever:            rr,
 		remoteReadSampleLimit:     remoteReadSampleLimit,
@@ -244,22 +246,32 @@ func NewAPI(
 	}
 }
 
+func setUnavailStatusOnTSDBNotReady(r apiFuncResult) apiFuncResult {
+	if r.err != nil && errors.Cause(r.err.err) == tsdb.ErrNotReady {
+		r.err.typ = errorUnavailable
+	}
+	return r
+}
+
 // Register the API's endpoints in the given router.
 func (api *API) Register(r *route.Router) {
 	wrap := func(f apiFunc) http.HandlerFunc {
 		hf := http.HandlerFunc(func(w http.ResponseWriter, r *http.Request) {
 			httputil.SetCORS(w, api.CORSOrigin, r)
-			result := f(r)
+			result := setUnavailStatusOnTSDBNotReady(f(r))
 			if result.finalizer != nil {
 				defer result.finalizer()
 			}
 			if result.err != nil {
 				api.respondError(w, result.err, result.data)
-			} else if result.data != nil {
-				api.respond(w, result.data, result.warnings)
-			} else {
-				w.WriteHeader(http.StatusNoContent)
+				return
 			}
+
+			if result.data != nil {
+				api.respond(w, result.data, result.warnings)
+				return
+			}
+			w.WriteHeader(http.StatusNoContent)
 		})
 		return api.ready(httputil.CompressionHandler{
 			Handler: hf,
@@ -1124,29 +1136,27 @@ type tsdbStatus struct {
 	SeriesCountByLabelValuePair []stat `json:"seriesCountByLabelValuePair"`
 }
 
-func (api *API) serveTSDBStatus(r *http.Request) apiFuncResult {
-	db := api.db()
-	if db == nil {
-		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("TSDB not ready")}, nil, nil}
+func convertStats(stats []index.Stat) []stat {
+	result := make([]stat, 0, len(stats))
+	for _, item := range stats {
+		item := stat{Name: item.Name, Value: item.Count}
+		result = append(result, item)
 	}
-	convert := func(stats []index.Stat) []stat {
-		result := make([]stat, 0, len(stats))
-		for _, item := range stats {
-			item := stat{Name: item.Name, Value: item.Count}
-			result = append(result, item)
-		}
-		return result
+	return result
+}
+
+func (api *API) serveTSDBStatus(*http.Request) apiFuncResult {
+	s, err := api.db.Stats("__name__")
+	if err != nil {
+		return apiFuncResult{nil, &apiError{errorInternal, err}, nil, nil}
 	}
 
-	posting := db.Head().PostingsCardinalityStats(model.MetricNameLabel)
-	response := tsdbStatus{
-		SeriesCountByMetricName:     convert(posting.CardinalityMetricsStats),
-		LabelValueCountByLabelName:  convert(posting.CardinalityLabelStats),
-		MemoryInBytesByLabelName:    convert(posting.LabelValueStats),
-		SeriesCountByLabelValuePair: convert(posting.LabelValuePairsStats),
-	}
-
-	return apiFuncResult{response, nil, nil, nil}
+	return apiFuncResult{tsdbStatus{
+		SeriesCountByMetricName:     convertStats(s.IndexPostingStats.CardinalityMetricsStats),
+		LabelValueCountByLabelName:  convertStats(s.IndexPostingStats.CardinalityLabelStats),
+		MemoryInBytesByLabelName:    convertStats(s.IndexPostingStats.LabelValueStats),
+		SeriesCountByLabelValuePair: convertStats(s.IndexPostingStats.LabelValuePairsStats),
+	}, nil, nil, nil}
 }
 
 func (api *API) remoteRead(w http.ResponseWriter, r *http.Request) {
@@ -1322,11 +1332,6 @@ func (api *API) deleteSeries(r *http.Request) apiFuncResult {
 	if !api.enableAdmin {
 		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("admin APIs disabled")}, nil, nil}
 	}
-	db := api.db()
-	if db == nil {
-		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("TSDB not ready")}, nil, nil}
-	}
-
 	if err := r.ParseForm(); err != nil {
 		return apiFuncResult{nil, &apiError{errorBadData, errors.Wrap(err, "error parsing form values")}, nil, nil}
 	}
@@ -1348,8 +1353,7 @@ func (api *API) deleteSeries(r *http.Request) apiFuncResult {
 		if err != nil {
 			return apiFuncResult{nil, &apiError{errorBadData, err}, nil, nil}
 		}
-
-		if err := db.Delete(timestamp.FromTime(start), timestamp.FromTime(end), matchers...); err != nil {
+		if err := api.db.Delete(timestamp.FromTime(start), timestamp.FromTime(end), matchers...); err != nil {
 			return apiFuncResult{nil, &apiError{errorInternal, err}, nil, nil}
 		}
 	}
@@ -1372,13 +1376,8 @@ func (api *API) snapshot(r *http.Request) apiFuncResult {
 		}
 	}
 
-	db := api.db()
-	if db == nil {
-		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("TSDB not ready")}, nil, nil}
-	}
-
 	var (
-		snapdir = filepath.Join(db.Dir(), "snapshots")
+		snapdir = filepath.Join(api.dbDir, "snapshots")
 		name    = fmt.Sprintf("%s-%x",
 			time.Now().UTC().Format("20060102T150405Z0700"),
 			rand.Int())
@@ -1387,7 +1386,7 @@ func (api *API) snapshot(r *http.Request) apiFuncResult {
 	if err := os.MkdirAll(dir, 0777); err != nil {
 		return apiFuncResult{nil, &apiError{errorInternal, errors.Wrap(err, "create snapshot directory")}, nil, nil}
 	}
-	if err := db.Snapshot(dir, !skipHead); err != nil {
+	if err := api.db.Snapshot(dir, !skipHead); err != nil {
 		return apiFuncResult{nil, &apiError{errorInternal, errors.Wrap(err, "create snapshot")}, nil, nil}
 	}
 
@@ -1400,12 +1399,7 @@ func (api *API) cleanTombstones(r *http.Request) apiFuncResult {
 	if !api.enableAdmin {
 		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("admin APIs disabled")}, nil, nil}
 	}
-	db := api.db()
-	if db == nil {
-		return apiFuncResult{nil, &apiError{errorUnavailable, errors.New("TSDB not ready")}, nil, nil}
-	}
-
-	if err := db.CleanTombstones(); err != nil {
+	if err := api.db.CleanTombstones(); err != nil {
 		return apiFuncResult{nil, &apiError{errorInternal, err}, nil, nil}
 	}
 
diff --git a/web/api/v1/api_test.go b/web/api/v1/api_test.go
index 552fda467..e0c7c74f9 100644
--- a/web/api/v1/api_test.go
+++ b/web/api/v1/api_test.go
@@ -1892,32 +1892,24 @@ func TestStreamReadEndpoint(t *testing.T) {
 }
 
 type fakeDB struct {
-	err    error
-	closer func()
+	err error
 }
 
 func (f *fakeDB) CleanTombstones() error                               { return f.err }
 func (f *fakeDB) Delete(mint, maxt int64, ms ...*labels.Matcher) error { return f.err }
-func (f *fakeDB) Dir() string {
-	dir, _ := ioutil.TempDir("", "fakeDB")
-	f.closer = func() {
-		os.RemoveAll(dir)
-	}
-	return dir
-}
-func (f *fakeDB) Snapshot(dir string, withHead bool) error { return f.err }
-func (f *fakeDB) Head() *tsdb.Head {
+func (f *fakeDB) Snapshot(dir string, withHead bool) error             { return f.err }
+func (f *fakeDB) Stats(statsByLabelName string) (*tsdb.Stats, error) {
 	h, _ := tsdb.NewHead(nil, nil, nil, 1000, tsdb.DefaultStripeSize)
-	return h
+	return h.Stats(statsByLabelName), nil
 }
 
 func TestAdminEndpoints(t *testing.T) {
-	tsdb, tsdbWithError := &fakeDB{}, &fakeDB{err: errors.New("some error")}
+	tsdb, tsdbWithError, tsdbNotReady := &fakeDB{}, &fakeDB{err: errors.New("some error")}, &fakeDB{err: errors.Wrap(tsdb.ErrNotReady, "wrap")}
 	snapshotAPI := func(api *API) apiFunc { return api.snapshot }
 	cleanAPI := func(api *API) apiFunc { return api.cleanTombstones }
 	deleteAPI := func(api *API) apiFunc { return api.deleteSeries }
 
-	for i, tc := range []struct {
+	for _, tc := range []struct {
 		db          *fakeDB
 		enableAdmin bool
 		endpoint    func(api *API) apiFunc
@@ -1965,7 +1957,7 @@ func TestAdminEndpoints(t *testing.T) {
 			errType: errorInternal,
 		},
 		{
-			db:          nil,
+			db:          tsdbNotReady,
 			enableAdmin: true,
 			endpoint:    snapshotAPI,
 
@@ -1994,7 +1986,7 @@ func TestAdminEndpoints(t *testing.T) {
 			errType: errorInternal,
 		},
 		{
-			db:          nil,
+			db:          tsdbNotReady,
 			enableAdmin: true,
 			endpoint:    cleanAPI,
 
@@ -2064,37 +2056,31 @@ func TestAdminEndpoints(t *testing.T) {
 			errType: errorInternal,
 		},
 		{
-			db:          nil,
+			db:          tsdbNotReady,
 			enableAdmin: true,
 			endpoint:    deleteAPI,
+			values:      map[string][]string{"match[]": {"up"}},
 
 			errType: errorUnavailable,
 		},
 	} {
 		tc := tc
-		t.Run(fmt.Sprintf("%d", i), func(t *testing.T) {
+		t.Run("", func(t *testing.T) {
+			dir, _ := ioutil.TempDir("", "fakeDB")
+			defer testutil.Ok(t, os.RemoveAll(dir))
+
 			api := &API{
-				db: func() TSDBAdmin {
-					if tc.db != nil {
-						return tc.db
-					}
-					return nil
-				},
+				db:          tc.db,
+				dbDir:       dir,
 				ready:       func(f http.HandlerFunc) http.HandlerFunc { return f },
 				enableAdmin: tc.enableAdmin,
 			}
-			defer func() {
-				if tc.db != nil && tc.db.closer != nil {
-					tc.db.closer()
-				}
-			}()
 
 			endpoint := tc.endpoint(api)
 			req, err := http.NewRequest(tc.method, fmt.Sprintf("?%s", tc.values.Encode()), nil)
-			if err != nil {
-				t.Fatalf("Error when creating test request: %s", err)
-			}
-			res := endpoint(req)
+			testutil.Ok(t, err)
+
+			res := setUnavailStatusOnTSDBNotReady(endpoint(req))
 			assertAPIError(t, res.err, tc.errType)
 		})
 	}
@@ -2504,14 +2490,7 @@ func TestTSDBStatus(t *testing.T) {
 	} {
 		tc := tc
 		t.Run(fmt.Sprintf("%d", i), func(t *testing.T) {
-			api := &API{
-				db: func() TSDBAdmin {
-					if tc.db != nil {
-						return tc.db
-					}
-					return nil
-				},
-			}
+			api := &API{db: tc.db}
 			endpoint := tc.endpoint(api)
 			req, err := http.NewRequest(tc.method, fmt.Sprintf("?%s", tc.values.Encode()), nil)
 			if err != nil {
diff --git a/web/api/v2/api.go b/web/api/v2/api.go
index b7c752baa..63cdacd79 100644
--- a/web/api/v2/api.go
+++ b/web/api/v2/api.go
@@ -26,7 +26,6 @@ import (
 
 	"github.com/grpc-ecosystem/grpc-gateway/runtime"
 	"github.com/pkg/errors"
-
 	"google.golang.org/grpc"
 	"google.golang.org/grpc/codes"
 	"google.golang.org/grpc/status"
@@ -40,16 +39,19 @@ import (
 // API encapsulates all API services.
 type API struct {
 	enableAdmin bool
-	db          func() *tsdb.DB
+	db          TSDBAdmin
+	dbDir       string
 }
 
 // New returns a new API object.
 func New(
-	db func() *tsdb.DB,
+	db TSDBAdmin,
+	dbDir string,
 	enableAdmin bool,
 ) *API {
 	return &API{
 		db:          db,
+		dbDir:       dbDir,
 		enableAdmin: enableAdmin,
 	}
 }
@@ -57,7 +59,7 @@ func New(
 // RegisterGRPC registers all API services with the given server.
 func (api *API) RegisterGRPC(srv *grpc.Server) {
 	if api.enableAdmin {
-		pb.RegisterAdminServer(srv, NewAdmin(api.db))
+		pb.RegisterAdminServer(srv, NewAdmin(api.db, api.dbDir))
 	} else {
 		pb.RegisterAdminServer(srv, &AdminDisabled{})
 	}
@@ -133,13 +135,21 @@ func (s *AdminDisabled) DeleteSeries(_ context.Context, r *pb.SeriesDeleteReques
 	return nil, errAdminDisabled
 }
 
+// TSDBAdmin defines the tsdb interfaces used by the v1 API for admin operations as well as statistics.
+type TSDBAdmin interface {
+	CleanTombstones() error
+	Delete(mint, maxt int64, ms ...*labels.Matcher) error
+	Snapshot(dir string, withHead bool) error
+}
+
 // Admin provides an administration interface to Prometheus.
 type Admin struct {
-	db func() *tsdb.DB
+	db    TSDBAdmin
+	dbDir string
 }
 
 // NewAdmin returns a Admin server.
-func NewAdmin(db func() *tsdb.DB) *Admin {
+func NewAdmin(db TSDBAdmin, dbDir string) *Admin {
 	return &Admin{
 		db: db,
 	}
@@ -147,12 +157,8 @@ func NewAdmin(db func() *tsdb.DB) *Admin {
 
 // TSDBSnapshot implements pb.AdminServer.
 func (s *Admin) TSDBSnapshot(_ context.Context, req *pb.TSDBSnapshotRequest) (*pb.TSDBSnapshotResponse, error) {
-	db := s.db()
-	if db == nil {
-		return nil, errTSDBNotReady
-	}
 	var (
-		snapdir = filepath.Join(db.Dir(), "snapshots")
+		snapdir = filepath.Join(s.dbDir, "snapshots")
 		name    = fmt.Sprintf("%s-%x",
 			time.Now().UTC().Format("20060102T150405Z0700"),
 			rand.Int())
@@ -161,7 +167,11 @@ func (s *Admin) TSDBSnapshot(_ context.Context, req *pb.TSDBSnapshotRequest) (*p
 	if err := os.MkdirAll(dir, 0777); err != nil {
 		return nil, status.Errorf(codes.Internal, "created snapshot directory: %s", err)
 	}
-	if err := db.Snapshot(dir, !req.SkipHead); err != nil {
+	if err := s.db.Snapshot(dir, !req.SkipHead); err != nil {
+		if errors.Cause(err) == tsdb.ErrNotReady {
+			return nil, errTSDBNotReady
+		}
+
 		return nil, status.Errorf(codes.Internal, "create snapshot: %s", err)
 	}
 	return &pb.TSDBSnapshotResponse{Name: name}, nil
@@ -169,12 +179,10 @@ func (s *Admin) TSDBSnapshot(_ context.Context, req *pb.TSDBSnapshotRequest) (*p
 
 // TSDBCleanTombstones implements pb.AdminServer.
 func (s *Admin) TSDBCleanTombstones(_ context.Context, _ *pb.TSDBCleanTombstonesRequest) (*pb.TSDBCleanTombstonesResponse, error) {
-	db := s.db()
-	if db == nil {
-		return nil, errTSDBNotReady
-	}
-
-	if err := db.CleanTombstones(); err != nil {
+	if err := s.db.CleanTombstones(); err != nil {
+		if errors.Cause(err) == tsdb.ErrNotReady {
+			return nil, errTSDBNotReady
+		}
 		return nil, status.Errorf(codes.Internal, "clean tombstones: %s", err)
 	}
 
@@ -212,11 +220,10 @@ func (s *Admin) DeleteSeries(_ context.Context, r *pb.SeriesDeleteRequest) (*pb.
 
 		matchers = append(matchers, lm)
 	}
-	db := s.db()
-	if db == nil {
-		return nil, errTSDBNotReady
-	}
-	if err := db.Delete(timestamp.FromTime(mint), timestamp.FromTime(maxt), matchers...); err != nil {
+	if err := s.db.Delete(timestamp.FromTime(mint), timestamp.FromTime(maxt), matchers...); err != nil {
+		if errors.Cause(err) == tsdb.ErrNotReady {
+			return nil, errTSDBNotReady
+		}
 		return nil, status.Error(codes.Internal, err.Error())
 	}
 	return &pb.SeriesDeleteResponse{}, nil
diff --git a/web/federate.go b/web/federate.go
index ebed25dc4..4815a5a16 100644
--- a/web/federate.go
+++ b/web/federate.go
@@ -20,10 +20,12 @@ import (
 
 	"github.com/go-kit/kit/log/level"
 	"github.com/gogo/protobuf/proto"
+	"github.com/pkg/errors"
 	"github.com/prometheus/client_golang/prometheus"
 	dto "github.com/prometheus/client_model/go"
 	"github.com/prometheus/common/expfmt"
 	"github.com/prometheus/common/model"
+	"github.com/prometheus/prometheus/tsdb"
 
 	"github.com/prometheus/prometheus/pkg/labels"
 	"github.com/prometheus/prometheus/pkg/timestamp"
@@ -78,6 +80,10 @@ func (h *Handler) federation(w http.ResponseWriter, req *http.Request) {
 	q, err := h.localStorage.Querier(req.Context(), mint, maxt)
 	if err != nil {
 		federationErrors.Inc()
+		if errors.Cause(err) == tsdb.ErrNotReady {
+			http.Error(w, err.Error(), http.StatusServiceUnavailable)
+			return
+		}
 		http.Error(w, err.Error(), http.StatusInternalServerError)
 		return
 	}
diff --git a/web/federate_test.go b/web/federate_test.go
index ffb721f93..8f9e86ab4 100644
--- a/web/federate_test.go
+++ b/web/federate_test.go
@@ -15,16 +15,22 @@ package web
 
 import (
 	"bytes"
+	"context"
+	"net/http"
 	"net/http/httptest"
 	"sort"
 	"strings"
 	"testing"
 	"time"
 
+	"github.com/pkg/errors"
 	"github.com/prometheus/common/model"
 	"github.com/prometheus/prometheus/config"
 	"github.com/prometheus/prometheus/pkg/labels"
 	"github.com/prometheus/prometheus/promql"
+	"github.com/prometheus/prometheus/storage"
+	"github.com/prometheus/prometheus/tsdb"
+	"github.com/prometheus/prometheus/util/testutil"
 )
 
 var scenarios = map[string]struct {
@@ -199,7 +205,7 @@ func TestFederation(t *testing.T) {
 	}
 
 	h := &Handler{
-		localStorage:  suite.Storage(),
+		localStorage:  &dbAdapter{suite.TSDB()},
 		lookbackDelta: 5 * time.Minute,
 		now:           func() model.Time { return 101 * 60 * 1000 }, // 101min after epoch.
 		config: &config.Config{
@@ -208,16 +214,59 @@ func TestFederation(t *testing.T) {
 	}
 
 	for name, scenario := range scenarios {
-		h.config.GlobalConfig.ExternalLabels = scenario.externalLabels
-		req := httptest.NewRequest("GET", "http://example.org/federate?"+scenario.params, nil)
-		res := httptest.NewRecorder()
-		h.federation(res, req)
-		if got, want := res.Code, scenario.code; got != want {
-			t.Errorf("Scenario %q: got code %d, want %d", name, got, want)
-		}
-		if got, want := normalizeBody(res.Body), scenario.body; got != want {
-			t.Errorf("Scenario %q: got body\n%s\n, want\n%s\n", name, got, want)
-		}
+		t.Run(name, func(t *testing.T) {
+			h.config.GlobalConfig.ExternalLabels = scenario.externalLabels
+			req := httptest.NewRequest("GET", "http://example.org/federate?"+scenario.params, nil)
+			res := httptest.NewRecorder()
+
+			h.federation(res, req)
+			testutil.Equals(t, scenario.code, res.Code)
+			testutil.Equals(t, scenario.body, normalizeBody(res.Body))
+		})
+	}
+}
+
+type notReadyReadStorage struct {
+	LocalStorage
+}
+
+func (notReadyReadStorage) Querier(context.Context, int64, int64) (storage.Querier, error) {
+	return nil, errors.Wrap(tsdb.ErrNotReady, "wrap")
+}
+
+func (notReadyReadStorage) StartTime() (int64, error) {
+	return 0, errors.Wrap(tsdb.ErrNotReady, "wrap")
+}
+
+func (notReadyReadStorage) Stats(string) (*tsdb.Stats, error) {
+	return nil, errors.Wrap(tsdb.ErrNotReady, "wrap")
+}
+
+// Regression test for https://github.com/prometheus/prometheus/issues/7181.
+func TestFederation_NotReady(t *testing.T) {
+	h := &Handler{
+		localStorage:  notReadyReadStorage{},
+		lookbackDelta: 5 * time.Minute,
+		now:           func() model.Time { return 101 * 60 * 1000 }, // 101min after epoch.
+		config: &config.Config{
+			GlobalConfig: config.GlobalConfig{},
+		},
+	}
+
+	for name, scenario := range scenarios {
+		t.Run(name, func(t *testing.T) {
+			h.config.GlobalConfig.ExternalLabels = scenario.externalLabels
+			req := httptest.NewRequest("GET", "http://example.org/federate?"+scenario.params, nil)
+			res := httptest.NewRecorder()
+
+			h.federation(res, req)
+			if scenario.code == http.StatusBadRequest {
+				// Request are expected to be checked before DB readiness.
+				testutil.Equals(t, http.StatusBadRequest, res.Code)
+				return
+			}
+			testutil.Equals(t, http.StatusServiceUnavailable, res.Code)
+		})
 	}
 }
 
diff --git a/web/web.go b/web/web.go
index 7e377b49a..204bfaf27 100644
--- a/web/web.go
+++ b/web/web.go
@@ -166,6 +166,11 @@ func (m *metrics) instrumentHandler(handlerName string, handler http.HandlerFunc
 // PrometheusVersion contains build information about Prometheus.
 type PrometheusVersion = api_v1.PrometheusVersion
 
+type LocalStorage interface {
+	storage.Storage
+	api_v1.TSDBAdminStats
+}
+
 // Handler serves various HTTP endpoints of the Prometheus server
 type Handler struct {
 	logger log.Logger
@@ -178,9 +183,8 @@ type Handler struct {
 	queryEngine   *promql.Engine
 	lookbackDelta time.Duration
 	context       context.Context
-	tsdb          func() *tsdb.DB
 	storage       storage.Storage
-	localStorage  storage.Storage
+	localStorage  LocalStorage
 	notifier      *notifier.Manager
 
 	apiV1 *api_v1.API
@@ -214,9 +218,10 @@ func (h *Handler) ApplyConfig(conf *config.Config) error {
 // Options for the web Handler.
 type Options struct {
 	Context               context.Context
-	TSDB                  func() *tsdb.DB
 	TSDBRetentionDuration model.Duration
+	TSDBDir               string
 	TSDBMaxBytes          units.Base2Bytes
+	LocalStorage          LocalStorage
 	Storage               storage.Storage
 	QueryEngine           *promql.Engine
 	LookbackDelta         time.Duration
@@ -283,9 +288,8 @@ func New(logger log.Logger, o *Options) *Handler {
 		ruleManager:   o.RuleManager,
 		queryEngine:   o.QueryEngine,
 		lookbackDelta: o.LookbackDelta,
-		tsdb:          o.TSDB,
 		storage:       o.Storage,
-		localStorage:  o.TSDB(),
+		localStorage:  o.LocalStorage,
 		notifier:      o.Notifier,
 
 		now: model.Now,
@@ -309,9 +313,8 @@ func New(logger log.Logger, o *Options) *Handler {
 			Scheme:        o.ExternalURL.Scheme,
 		},
 		h.testReady,
-		func() api_v1.TSDBAdmin {
-			return h.options.TSDB()
-		},
+		h.options.LocalStorage,
+		h.options.TSDBDir,
 		h.options.EnableAdminAPI,
 		logger,
 		h.ruleManager,
@@ -538,7 +541,8 @@ func (h *Handler) Run(ctx context.Context) error {
 		grpcSrv = grpc.NewServer()
 	)
 	av2 := api_v2.New(
-		h.options.TSDB,
+		h.options.LocalStorage,
+		h.options.TSDBDir,
 		h.options.EnableAdminAPI,
 	)
 	av2.RegisterGRPC(grpcSrv)
@@ -789,13 +793,22 @@ func (h *Handler) status(w http.ResponseWriter, r *http.Request) {
 			status.LastConfigTime = time.Unix(int64(toFloat64(mF)), 0).UTC()
 		}
 	}
-	db := h.tsdb()
+
 	startTime := time.Now().UnixNano()
-	status.Stats = db.Head().PostingsCardinalityStats("__name__")
+	s, err := h.localStorage.Stats("__name__")
+	if err != nil {
+		if errors.Cause(err) == tsdb.ErrNotReady {
+			http.Error(w, tsdb.ErrNotReady.Error(), http.StatusServiceUnavailable)
+			return
+		}
+		http.Error(w, fmt.Sprintf("error gathering local storage statistics: %s", err), http.StatusInternalServerError)
+		return
+	}
 	status.Duration = fmt.Sprintf("%.3f", float64(time.Now().UnixNano()-startTime)/float64(1e9))
-	status.NumSeries = db.Head().NumSeries()
-	status.MaxTime = db.Head().MaxTime()
-	status.MinTime = db.Head().MaxTime()
+	status.Stats = s.IndexPostingStats
+	status.NumSeries = s.NumSeries
+	status.MaxTime = s.MaxTime
+	status.MinTime = s.MinTime
 
 	h.executeTemplate(w, "status.html", status)
 }
diff --git a/web/web_test.go b/web/web_test.go
index a34e17ca6..23fbf3e49 100644
--- a/web/web_test.go
+++ b/web/web_test.go
@@ -41,6 +41,7 @@ func TestMain(m *testing.M) {
 	os.Setenv("no_proxy", "localhost,127.0.0.1,0.0.0.0,:")
 	os.Exit(m.Run())
 }
+
 func TestGlobalURL(t *testing.T) {
 	opts := &Options{
 		ListenAddress: ":9090",
@@ -89,15 +90,21 @@ func TestGlobalURL(t *testing.T) {
 	}
 }
 
+type dbAdapter struct {
+	*tsdb.DB
+}
+
+func (a *dbAdapter) Stats(statsByLabelName string) (*tsdb.Stats, error) {
+	return a.Head().Stats(statsByLabelName), nil
+}
+
 func TestReadyAndHealthy(t *testing.T) {
 	t.Parallel()
 	dbDir, err := ioutil.TempDir("", "tsdb-ready")
-
 	testutil.Ok(t, err)
+	defer testutil.Ok(t, os.RemoveAll(dbDir))
 
-	defer os.RemoveAll(dbDir)
 	db, err := tsdb.Open(dbDir, nil, nil, nil)
-
 	testutil.Ok(t, err)
 
 	opts := &Options{
@@ -106,13 +113,14 @@ func TestReadyAndHealthy(t *testing.T) {
 		MaxConnections: 512,
 		Context:        nil,
 		Storage:        nil,
+		LocalStorage:   &dbAdapter{db},
+		TSDBDir:        dbDir,
 		QueryEngine:    nil,
 		ScrapeManager:  &scrape.Manager{},
 		RuleManager:    &rules.Manager{},
 		Notifier:       nil,
 		RoutePrefix:    "/",
 		EnableAdminAPI: true,
-		TSDB:           func() *tsdb.DB { return db },
 		ExternalURL: &url.URL{
 			Scheme: "http",
 			Host:   "localhost:9090",
@@ -136,6 +144,9 @@ func TestReadyAndHealthy(t *testing.T) {
 		}
 	}()
 
+	// TODO(bwplotka): Those tests create tons of new connection and memory that is never cleaned.
+	// Close and exhaust all response bodies.
+
 	// Give some time for the web goroutine to run since we need the server
 	// to be up before starting tests.
 	time.Sleep(5 * time.Second)
@@ -282,13 +293,10 @@ func TestReadyAndHealthy(t *testing.T) {
 func TestRoutePrefix(t *testing.T) {
 	t.Parallel()
 	dbDir, err := ioutil.TempDir("", "tsdb-ready")
-
 	testutil.Ok(t, err)
-
-	defer os.RemoveAll(dbDir)
+	defer testutil.Ok(t, os.RemoveAll(dbDir))
 
 	db, err := tsdb.Open(dbDir, nil, nil, nil)
-
 	testutil.Ok(t, err)
 
 	opts := &Options{
@@ -296,6 +304,8 @@ func TestRoutePrefix(t *testing.T) {
 		ReadTimeout:    30 * time.Second,
 		MaxConnections: 512,
 		Context:        nil,
+		TSDBDir:        dbDir,
+		LocalStorage:   &dbAdapter{db},
 		Storage:        nil,
 		QueryEngine:    nil,
 		ScrapeManager:  nil,
@@ -307,7 +317,6 @@ func TestRoutePrefix(t *testing.T) {
 			Host:   "localhost.localdomain:9090",
 			Scheme: "http",
 		},
-		TSDB: func() *tsdb.DB { return db },
 	}
 
 	opts.Flags = map[string]string{}
@@ -399,7 +408,6 @@ func TestDebugHandler(t *testing.T) {
 				Host:   "localhost.localdomain:9090",
 				Scheme: "http",
 			},
-			TSDB: func() *tsdb.DB { return nil },
 		}
 		handler := New(nil, opts)
 		handler.Ready()
@@ -426,7 +434,6 @@ func TestHTTPMetrics(t *testing.T) {
 			Host:   "localhost.localdomain:9090",
 			Scheme: "http",
 		},
-		TSDB: func() *tsdb.DB { return nil },
 	})
 	getReady := func() int {
 		t.Helper()