diff --git a/cmd/prometheus/main_test.go b/cmd/prometheus/main_test.go
index f4fe3855c..03f3a9bc3 100644
--- a/cmd/prometheus/main_test.go
+++ b/cmd/prometheus/main_test.go
@@ -126,12 +126,9 @@ func TestFailedStartupExitCode(t *testing.T) {
 	require.Error(t, err)
 
 	var exitError *exec.ExitError
-	if errors.As(err, &exitError) {
-		status := exitError.Sys().(syscall.WaitStatus)
-		require.Equal(t, expectedExitStatus, status.ExitStatus())
-	} else {
-		t.Errorf("unable to retrieve the exit status for prometheus: %v", err)
-	}
+	require.ErrorAs(t, err, &exitError)
+	status := exitError.Sys().(syscall.WaitStatus)
+	require.Equal(t, expectedExitStatus, status.ExitStatus())
 }
 
 type senderFunc func(alerts ...*notifier.Alert)
@@ -194,9 +191,7 @@ func TestSendAlerts(t *testing.T) {
 		tc := tc
 		t.Run(fmt.Sprintf("%d", i), func(t *testing.T) {
 			senderFunc := senderFunc(func(alerts ...*notifier.Alert) {
-				if len(tc.in) == 0 {
-					t.Fatalf("sender called with 0 alert")
-				}
+				require.NotEmpty(t, tc.in, "sender called with 0 alert")
 				require.Equal(t, tc.exp, alerts)
 			})
 			rules.SendAlerts(senderFunc, "http://localhost:9090")(context.TODO(), "up", tc.in...)
@@ -228,7 +223,7 @@ func TestWALSegmentSizeBounds(t *testing.T) {
 			go func() { done <- prom.Wait() }()
 			select {
 			case err := <-done:
-				t.Errorf("prometheus should be still running: %v", err)
+				require.Fail(t, "prometheus should be still running: %v", err)
 			case <-time.After(startupTime):
 				prom.Process.Kill()
 				<-done
@@ -239,12 +234,9 @@ func TestWALSegmentSizeBounds(t *testing.T) {
 		err = prom.Wait()
 		require.Error(t, err)
 		var exitError *exec.ExitError
-		if errors.As(err, &exitError) {
-			status := exitError.Sys().(syscall.WaitStatus)
-			require.Equal(t, expectedExitStatus, status.ExitStatus())
-		} else {
-			t.Errorf("unable to retrieve the exit status for prometheus: %v", err)
-		}
+		require.ErrorAs(t, err, &exitError)
+		status := exitError.Sys().(syscall.WaitStatus)
+		require.Equal(t, expectedExitStatus, status.ExitStatus())
 	}
 }
 
@@ -274,7 +266,7 @@ func TestMaxBlockChunkSegmentSizeBounds(t *testing.T) {
 			go func() { done <- prom.Wait() }()
 			select {
 			case err := <-done:
-				t.Errorf("prometheus should be still running: %v", err)
+				require.Fail(t, "prometheus should be still running: %v", err)
 			case <-time.After(startupTime):
 				prom.Process.Kill()
 				<-done
@@ -285,12 +277,9 @@ func TestMaxBlockChunkSegmentSizeBounds(t *testing.T) {
 		err = prom.Wait()
 		require.Error(t, err)
 		var exitError *exec.ExitError
-		if errors.As(err, &exitError) {
-			status := exitError.Sys().(syscall.WaitStatus)
-			require.Equal(t, expectedExitStatus, status.ExitStatus())
-		} else {
-			t.Errorf("unable to retrieve the exit status for prometheus: %v", err)
-		}
+		require.ErrorAs(t, err, &exitError)
+		status := exitError.Sys().(syscall.WaitStatus)
+		require.Equal(t, expectedExitStatus, status.ExitStatus())
 	}
 }
 
@@ -347,10 +336,8 @@ func getCurrentGaugeValuesFor(t *testing.T, reg prometheus.Gatherer, metricNames
 			}
 
 			require.Len(t, g.GetMetric(), 1)
-			if _, ok := res[m]; ok {
-				t.Error("expected only one metric family for", m)
-				t.FailNow()
-			}
+			_, ok := res[m]
+			require.False(t, ok, "expected only one metric family for", m)
 			res[m] = *g.GetMetric()[0].GetGauge().Value
 		}
 	}
diff --git a/cmd/prometheus/main_unix_test.go b/cmd/prometheus/main_unix_test.go
index 417d062d6..59c5fe2bc 100644
--- a/cmd/prometheus/main_unix_test.go
+++ b/cmd/prometheus/main_unix_test.go
@@ -23,6 +23,8 @@ import (
 	"testing"
 	"time"
 
+	"github.com/stretchr/testify/require"
+
 	"github.com/prometheus/prometheus/util/testutil"
 )
 
@@ -37,9 +39,7 @@ func TestStartupInterrupt(t *testing.T) {
 
 	prom := exec.Command(promPath, "-test.main", "--config.file="+promConfig, "--storage.tsdb.path="+t.TempDir(), "--web.listen-address=0.0.0.0"+port)
 	err := prom.Start()
-	if err != nil {
-		t.Fatalf("execution error: %v", err)
-	}
+	require.NoError(t, err)
 
 	done := make(chan error, 1)
 	go func() {
@@ -68,14 +68,11 @@ Loop:
 		time.Sleep(500 * time.Millisecond)
 	}
 
-	if !startedOk {
-		t.Fatal("prometheus didn't start in the specified timeout")
-	}
-	switch err := prom.Process.Kill(); {
-	case err == nil:
-		t.Errorf("prometheus didn't shutdown gracefully after sending the Interrupt signal")
-	case stoppedErr != nil && stoppedErr.Error() != "signal: interrupt":
-		// TODO: find a better way to detect when the process didn't exit as expected!
-		t.Errorf("prometheus exited with an unexpected error: %v", stoppedErr)
+	require.True(t, startedOk, "prometheus didn't start in the specified timeout")
+	err = prom.Process.Kill()
+	require.Error(t, err, "prometheus didn't shutdown gracefully after sending the Interrupt signal")
+	// TODO - find a better way to detect when the process didn't exit as expected!
+	if stoppedErr != nil {
+		require.EqualError(t, stoppedErr, "signal: interrupt", "prometheus exited with an unexpected error: %v", stoppedErr)
 	}
 }
diff --git a/cmd/promtool/unittest_test.go b/cmd/promtool/unittest_test.go
index b8170d784..971ddb40c 100644
--- a/cmd/promtool/unittest_test.go
+++ b/cmd/promtool/unittest_test.go
@@ -16,6 +16,8 @@ package main
 import (
 	"testing"
 
+	"github.com/stretchr/testify/require"
+
 	"github.com/prometheus/prometheus/promql"
 )
 
@@ -178,9 +180,8 @@ func TestRulesUnitTestRun(t *testing.T) {
 	}
 	for _, tt := range tests {
 		t.Run(tt.name, func(t *testing.T) {
-			if got := RulesUnitTest(tt.queryOpts, tt.args.run, false, tt.args.files...); got != tt.want {
-				t.Errorf("RulesUnitTest() = %v, want %v", got, tt.want)
-			}
+			got := RulesUnitTest(tt.queryOpts, tt.args.run, false, tt.args.files...)
+			require.Equal(t, tt.want, got)
 		})
 	}
 }